![]() ![]() You cannot say the same of Cheetah.Īnd the Blender integration with Untity is just perfect, I would say it is just the best currently available, better than with Maya, 3dMax or Cheetah. Beginning by a good set of animation tools (try to animate a simple walk in Cheetah and you will understand), a much better UV mapping, tons of tutorials about anything you could need to learn, and a very strong and quick developing process which has turned it into a really competent 3D suit, currently comparable to any other profesional animation tool. But it lacks a lot of other usefull features Blender offers (yes, also for game work). And I think Cheetah is a nice subdivision modeller, and now it has also a nice renderer. And if you are beginning with 3D, Maya or 3dMax UIs are equally odd, difficult and un-intuitive as Blender's one. Well, IMHO, if you don´t know how an aplication works, your opinion about it is not very informative, nor usefull. Almost all the criticism you can read about Blender begin saying "I never could pass the odd UI.". The cheetah gang is very quick and active in this forum, as you allready should have noticedīut the truth is that Blender is a much more robust and mature 3D aplication, and his integration with Unity is much better than the cheetah one. Unity is a great tool, but keep in mind that if you aren't readily prepared for the complexities of working with 3D content, it'll be very easy to find yourself getting lost within it and discouraged by it. (This is something I actually do myself.) Once you understand the tools and have a working prototype, it'll make bridging the gap into 3D through Unity a much simpler process. This will give you a chance to flesh out your basic game concepts while you're learning more about the basics of 3D animation and modeling. ![]() If you have some idea for a game, you might want to try using something like Flash as a means of creating a working prototype before jumping directly into Unity. Am I correct in assuming you have some experience with Flash in some form? In the meanwhile, you mentioned you've used Swift3D before. Such concepts may prove vital when you start bridging over into apps like Unity, where you actually interact with the content you've created. It's not too expensive, there's a lot of great 3rd party support for the software and the software itself is a good introduction to working with important 3D modeling and animation concepts. ![]() Personally, I've been a fan of software like Carrara Studio Pro from DAZ Productions. The documentation tends to be better and the interfaces are less taxing on the mind. If you are literally just starting out in 3D, you might be better off using a more polished commercial, consumer-level 3D package. A number of the tools within Cheetah 3D aren't quite as intuitive as the could be, which often leaves you with a number of head-scratching "what do I do now?" situations. If anything, the problems you'll likely get stuck on are with Cheetah3D itself. Well, Cheetah3D does work well with Unity in a number of areas. ![]()
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![]() ![]() When I ran it, I had to add sudo to the start of each line. Hit up this page and you’ll see the following, do it. Installation from here is rather easy, following But first, ComposerĬakePHP uses composer for installation, so we’ll need to install composer first. ![]() Then then type the following to confirm the path: This will refresh your terminal windows to use this new profile. This will set the php command to be set to MAMP’s PHP instead of the PHP that came with Mac. bash_profile and add the following line:Įxport PATH =/Applications/MAMP/bin/php/php7.3.7/bin:$PATH In Terminal, go to your home directory, then edit. I came across this lovely blog post which helped. It may be possible to install it all, I trust it is, but this was much easier and faster. The PHP that comes with Mac doesn’t have the necessary extensions installed. If you tried to install CakePHP right now, you’d get a headache, which is what I cried over for a while. Have fun working with Laravel.Continuing in the trend of “not knowing Mac well enough”, it appears Mac OSX Mojave comes with PHP, but a slightly different configured version. You should see the Laravel home page.įantastic Job Done ! You have now installed Laravel with Mamp on Mac OSX. Then it will show you the url where project is running something like, Go to the browser and hit this url. Navigate to the project you just created. Once the Laravel installation is finished, Now it's time to run the Laravel web application. This will start downloading the Laravel software and other required dependencies. Navigate to Applications/MAMP/htdocs folder in terminal & run the following command composer create -project laravel /laravel myProject "5.5.*" In case it doesn't output the correct path, try closing the terminal window (exit fully) and open again, it should apply the changes (Restart in short).Īlright, we are now all setup to install Laravel with MAMP.If everything was successful, It should output the new path to MAMP PHP install In Terminal, type in which php again and look for the updated string.In Terminal, run source ~/.bash_profile.(You can check the latest PHP version available in your MAMP directory (/Applications/MAMP/bin/php) Type i and then paste the following at the top of the file:Įxport PATH=/Applications/MAMP/bin/php/php7.2.8/bin:$PATH.Within the Terminal, run vim ~/.bash_profile.But if not then you either have to upgrade your php version on local mac, Or we can switch local PHP to use our MAMP php version which is greater than 7.1.3 If the version returned by this command is >=7.1.3, then you are good to go. 5.7 requires PHP >=7.1.3, Although the latest MAMP will have the latest PHP, it might be the case that the PHP installed local to your MAC machine is old.Ĭheck by running the following command on terminal. Test it out by command composer -v on terminal. That's it, you now have composer on your MAC. Move the composer to /usr/local/bin/composer mv composer.phar /usr/local/bin/composer If not follow below steps.ĭownload composer installer by this command in terminal curl -sS | php Open your terminal and type out command composer -v, If this gives your the composer version that means you have composer already installed on your machine. Laravel makes use of composer for dependency management, So we need to make sure we have that installed in our system. If the MAMP is installed correctly and the server started without any errors, you should see the following page on accessing localhost in your browser. You should see a MAMP directory created with following contents.Ĭlick on MAMP to start the MAMP Control Panel (Which looks like below image)Ĭlick on Start Servers to Start the MAMP Server. ![]() ![]() Once the installation is successfully completed, You can now go ahead to start the MAMP. The package will start writing files in your MAC. Go through the installation with all the steps. Click the package to start installing MAMP.Ĭlick on Continue to proceed with Installation. This will download a *.pkg installer on your MAC. Go to MAMP official website and choose to download MAMP for OSX (Mac) MAMP provides them with all the tools they need to run WordPress on their desktop PC for testing or development purposes. MAMP is a free, local server environment that can be installed under macOS and Windows with just a few clicks. The first step is to make sure you have MAMP installed on your Mac. In this tutorial we will go over step by step on How to Install Laravel with MAMP on Mac OSX. ![]() ![]() ![]() ![]() They are plans for good and not disaster, plans to give you a future filled with hope." "I know the plans that I have for you, declares the Lord. Always try to be kind to each other and to everyone else. Make sure that nobody pays back one wrong act with another. If you honor your father and mother, things will go well for you, and you will have a long life on earth.įor the Lord sees not as man sees: man looks on the outward appearance, but the Lord looks on the heart. This is the first commandment with a promise. Minnesota Cuke and the Search for Noah's Umbrellaīeing afraid of people can get you into trouble, but if you trust in the Lord, you will be Safe. If you know what is right to do, but you do not do it, you sin.Īnd so after waiting patiently, Abraham received what was promised.Įnthusiasm without knowledge is no good: haste makes mistakes. Tomato Sawyer and Huckleberry Larry's Big River Rescue How great is the love the Father has lavished on us, the we should be called Children of God!Ī happy heart is good medicine and a cheerful mind works healing. You created the deepest parts of my being, You put me together inside my mother's body. The Lord is my strength and my shield, my heart trusts in him and I am helped. Seek his will in all you do and he will direct your paths.Īnyone who loves God must also love his brothers and sisters. ![]() Trust in the Lord with all your heart and do not depend on your own understanding. Keep alert and pray, otherwise temptation will overpower you for though the spirit is willing enough, the body is weak. Minnesota Cuke and the Search for Samson's Hairbrushīut I tell you, love your enemies and pray for those who persecute you.įor we are God's workmanship, created in Christ Jesus to do good works, which God prepared in advance for us to do.Ī friend loves at all times, and a brother is born for adversity. Honor one another above yourselves.Ĭome near to God and he will come near to you. You need to persevere so that when you have done the will of God, you will receive what he has promised.īe devoted to one another in brotherly love. I praise you because I am fearfully and wonderfully made. Who repents than over ninety-nine righteous persons who do not need toĪnd we know that God causes all things to work together for good to those who love God. That in the same way there will be more rejoicing in heaven over one sinner Together and says, 'Rejoice with me I have found my lost sheep.' I tell you Does he not leave the ninety-nine in the open countryĪnd go after the lost sheep until he finds it? And when he finds it, he joyfully "Then Jesus told them this parable: 'Suppose one of you has a hundred sheepĪnd loses one of them. "Love each other as brothers and sisters and honor others more than you do yourself."Īnd do not forget to do good and to share with others, for with such sacrifices God is pleased. ![]() Reckless words pierce like a sword, but the tongue of the wise brings healing. He who is greedy for gain troubles his own house. Stand Firm, and hold to the teaching we passed on to you. The Lord is my rock, my fortress, and my deliverer my God is my rock, in whom I take refuge, my shield and the horn of my salvation, my stronghold.Jesus answered, I tell you, not seven times, but seventy times seven. As David prayed in Psalm 18:1: “I love you, Lord, my strength. I wait upon You for Your definition of the “good thing” You will not withhold from me. Your Word promises “no good thing does He withhold from those that walk uprightly” (Psalm 84:11). Everyone needs to be reminded from time to time of the hope that God, Jesus, and the Bible offer to us in our daily lives.Ī Prayer for Hope: Lord, I maintain my hope in You and I hold onto the assurance that what I am praying for is already accomplished in the name of Jesus. When you need encouragement and refreshment for your soul, turn to these Scriptures from the Old and New Testaments that offer hope and encouragement. When you are facing tests of faith, even the strongest Christians can find it a challenge to find hope. Bible Verses about Hope - How is your hope? Does it bounce back after being hit? Does it cause you to doubt when you lose hope in a situation? God knows that we all struggle with finding and holding onto hope. ![]() ![]() ![]() Oh and colleagues designed the randomized, double-blind, placebo-controlled, phase 3 TOPAZ-1 trial to confirm whether adding durvalumab to chemotherapy confers meaningful benefits. 2īased on encouraging antitumor activity observed with durvalumab plus gemcitabine and cisplatin in a phase 2 trial, Dr. Based on encouraging antitumor activity observed with durvalumab plus gemcitabine and cisplatin in a phase 2 trial, Dr. ![]() Upon recognizing that BTCs display immunogenic features, investigators have increasingly explored immune checkpoint inhibitors as possible options for enhancing disease control and prolonging survival. For example, patients who receive first-line gemcitabine and cisplatin usually do not live beyond 12 months. For more than a decade, chemotherapy has been the best first- and second-line treatment option for patients with BTCs, even though responses are typically transient. TOPAZ-1 Rationale and DesignīTCs comprise a heterogeneous collection of rare, aggressive neoplasms, which together carry a very poor prognosis. Oh noted that these toxicities are consistent with those typically observed with gemcitabine and cisplatin. The most common all-grade TRAEs observed in the durvalumab arm were hematologic events, such as anemia (48.2%) and neutropenia (31.7%), along with nausea (40.2%). Likewise, similar proportions of patients treated with durvalumab and those treated with placebo discontinued study medication due to TRAEs (8.9% vs 11.4%), with a slight advantage in favor of durvalumab. There was little difference in the incidence of grade 3/4 treatment-related adverse events (TRAEs) between patients who received durvalumab and those who received placebo (62.7% vs 64.9%). In terms of safety, durvalumab proved to be well tolerated when combined with chemotherapy. “It will be important to look at the subset analyses to try to determine if there are particular patients who will benefit or not benefit from this strategy so that we can really tailor treatment going forward,” Dr. In addition, separation between the survival curves widened over time, also consistent with the sustained survival benefits often achieved with immune checkpoint inhibitors in a subset of patients. Oh said is consistent with many other phase 3 clinical trials comparing immune checkpoint inhibitor/chemotherapy combinations against chemotherapy alone. Of note, separation in the survival curves for the 2 treatment arms did not occur until about 6 months after treatment initiation, which Dr. 001), as was the objective response rate (26.7% vs 18.7%). Progression-free survival was also greatly improved with chemoimmunotherapy vs chemotherapy alone (HR 0.75, 95% CI P =. Accordingly, it is likely to become the new standard of care for first-line therapy for many-if not the majority-of patients,” said Nilofer Azad, MD, of the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, who served as the discussant for the abstract.Īt the first interim analysis, treatment with durvalumab plus gemcitabine and cisplatin conferred a 20% reduction in the risk of death compared with gemcitabine and cisplatin alone, thus meeting the primary endpoint of the trial (HR 0.80, 95% CI P =. “This is the first trial in over a decade that has shown a survival benefit with the addition of another agent to gemcitabine and cisplatin. Principal investigator Do-Youn Oh, MD, PhD, of Seoul National University Hospital and Seoul National University College of Medicine, presented the study findings at the 2022 ASCO Gastrointestinal Cancers Symposium. TOPAZ-1, the first global phase 3 study to evaluate use of immunotherapy in the first-line setting in advanced biliary tract cancers (BTCs), demonstrated that adding the PD-L1 inhibitor durvalumab to gemcitabine and cisplatin-the current first-line standard of care-significantly improves overall survival and other efficacy outcomes without exacerbating toxicity ( Abstract 378). Adding durvalumab to gemcitabine and cisplatin significantly improved overall survival, progression-free survival, and objective response rate, without exacerbating toxicity.TOPAZ-1 represents the first phase 3 trial to demonstrate positive results with the addition of an immune checkpoint inhibitor to standard first-line chemotherapy in biliary tract cancer. ![]() ![]() ![]() "That's very refreshing," remarked Stuart. whipped off his cap, lay down on his stomach, and dipped up some of the cool refreshing drink, using his cap as a dipper. Frankly, I expect better than the following from a man who's written his own bloody book about grammar: Instead we just had this random meeting (which was another instance of unexplained phenomenon - why is she two inches tall, but otherwise a regular person? If we're being asked to accept that Stuart's situation is conceivable, why not just stick with that? Why mess with it like this?), for no particular reason.Īlso, I know it's a children's book, and a fairly old one at that, but let's have some standards of literature here. What was the point of that? I'd have made her another mouse person like Stuart, and maybe they could continue to journey together or something. They meet, try to have a date, it doesn't really work, she goes home, and he continues his journey. His encounter with Harriet, the two-inch-tall girl is also fairly random and fairly pointless. And how it becomes invisible is also entirely unexplained. From that point on, it's just Stuart's little car. The car goes invisible in its owner's office, crashes around for a while, and that's it. WTF? All of a sudden, this bit of complete outlandishness is just dropped into the story. But this thing has an invisibility button. OK, there again, maybe you could be crazy enough to build a model car that actually runs on gasoline and everything. Someone could be crazy enough to build a model ship that is fully functional, to the point of being crewable if only you could find a crew small enough. The things his father builds for him make sense, the fact that he wears doll clothes makes sense, and even his sailing of the model ship is conceivable. Maybe he got bored? In any case, it's kind of bizarre.Īlso contributing to my sense that he didn't really know what he was doing with this story is the fact that, for the most part, aside from the fact that Stuart is a mouse born to a human family, everything is basically, well, reasonably plausible. It was written earlier than the other two books included in this volume, so I don't know. It really feels unfinished, and I actually checked to see if maybe he died in the middle of writing it or something, but no. We just know he sets out on this quest, and that's it. We don't know how the Little family reacts to Stuart's departure, or if he ever makes it back. We don't find out if Stuart finds Margalo, or anything about what happens to Margalo. It's like White just stopped writing in the middle of the story. Only barely more cohesive, though, as it too consists of a series of basically unrelated escapade along his journey.Īnd then it just ends. The first half of it consists of largely unrelated, episodic adventures around New York, and then the second half develops a somewhat more cohesive plot as he embarks on his quest to find Margalo. However, the book kind of felt like White didn't really know what he was doing with it or where he was going with it. So I loved all the little contraptions and whatnot created to help Stuart function in a human-sized house. The premise is one I enjoy, as I've always been somewhat fascinated by unusually small things, and the notion of experiencing the world from the perspective of a very small being. (i am procrastinating from paper - must return) but this was as bad as 9/11, and the overripe pluot i just ate. rereading charlotte's web and trumpet of the swan was great - they can keep their five stars. In the mind of whatever perverted dreamer might loose the lightning, New York must hold a steady, irresistible charm." so now i blame him for 9/11, too. Of all targets New York has a certain clear priority. white: "He never stopped loving New York, calling it "a riddle in steel and stone," but he also prophetically saw the vulnerability of the city: "A single flight of planes no bigger than a wedge of geese can quickly end this island fantasy, burn the towers, crumble the bridges, turn the underground passages into lethal chambers, cremate millions. the premise is disgusting, the characters are either delusional or petty or just plain jerks, the story is flimsy, the central conflict is who-caresish. but that doesn't excuse the beginning or the middle of the book, both equally atrocious. white was a hypochondriac who was convinced he was about to die and wanted to get this out to the publishers before that happened. and i've since learned that the ending on this was rushed because e.b. now that i reread it for my paper, it gets what it deserves. i remember liking this book when i read it as a child, and i loved trumpet of the swan and charlotte's web like no other, so i just sense-memoried this into 4 stars. ![]() |